These new cosmetic procedures are based on advanced medical technology involving the separation of platelets from red blood cells. The PRF and PRP requires an extraction of a small amount of the patient’s blood, place it in a centrifuge that separates fibrin and platelets (that are crucial to wound healing) from blood cells and then insert this blood plasma that contains concentrated platelets, leukocytes, and growth factors into the skin or spreading it onto the skin after a laser therapy procedure to firm sagging skin and smooth wrinkles. This substance stimulates collagen production, skin renewal, cell migration, and tissue regeneration. The production of new skin cells rapidly fills in lined, tired skin and gives people undergoing this procedure the appearance of having an invasive facelift. PRF and PRP are considered very safe and effective facial rejuvenation procedures.
Platelet-rich Plasma (PRP) has experienced substantial growth in the aesthetic community over the last few years – it’s currently being used to rejuvenate the skin in “vampire facials” (it’s also commonly used with microneedling), in addition to assisting in hair restoration and wound healing. Platelet-Rich Plasma is a result of double spin method – a hard spin to separate red blood cells from everything everything else in the autologous (or whole) blood and a soft spin to separate the platelets and white blood cells. The result is Platelet-Rich Plasma (PRP), Platelet-Poor Plasma (PPP) and Red Blood Cells.
Platelet-rich Fibrin (PRF) is the next generation of the treatment and a valuable tool for plastic surgeons, dermatologists, and even dentists. PRF is a newer method, here after the first centrifugation, the middle layer is taken – which contains less platelets but more clotting factors. This gradually forms into a fibrin network and traps in the cytokines. It is then centrifuged in a PRF centrifuge resulting in PRF, a fibrin layer containing platelets and plasma.
- Tightens skin by accelerating collagen production
- Forms new blood vessels under the skin to give the skin glow
- Diminishes wrinkles and fine lines
- Improves skin tone and texture
- Reduces dark circles under the eyes and eye puffiness
- Ameliorates chronic rosacea
- Diminishes acne scars, sun damage, stretch marks
- PRF is 100% natural. It uses your body’s own platelets.
- The growth factors in PRF are your own anti-aging treatment, higher concentration of platelets, fibrin, and white blood cells, along with a small amount of stem cells
- PRF can be used anywhere on the body and face. It has been used in the medical field to promote faster healing following surgical procedures, such as bone grafts, dental implants, hair loss treatment, healing following cosmetic surgery procedures, and more.
- A longer lasting anti-aging treatment compared to PRP
- PRF can be combined with laser treatments for even greater improvement.
I recently had a PRF facial and can’t say enough about Dr.McLaurin as well as her office staff Jon, Kiyana and Aisha. Everyone is extremely friendly, kind and efficient. You immediately feel at ease when you enter the office and the laughter is a welcome bonus!!
Dr. McLaurin is a true professional!! I immediately sensed she loves her profession and truly cares about her clients. I never felt rushed!! She took time to examine my skin, explained the procedure and what to expect over the next few days/weeks.
I am now 2 weeks out from the procedure and am extremely pleased with the results!! My skin glows and feels incredible. It feels softer, plumper, with a decrease in the fine lines on my forehead and around my eyes and mouth. I would absolutely recommend Dr. McLaurin if you are interested in a PRF facial you will not be disappointed!!!
Although there are some basic similarities between platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), it is the differences between these two products that makes PRF (platelet-rich fibrin) stand out as a superior treatment option. Both of these products require blood to be taken from the patient. PRP requires more blood to be taken than PRF. Both of the products require the whole blood sample to be placed into a centrifuge, where the blood is then processed to help separate the blood into distinct layers. The PRF product is spun at a lower speed so that the layers of the blood do not separate out as distinctly. This allows some of the white blood cells and stem cells to remain within the platelet layer that is collected for treatment. Thus, there are more healing factors within PRF than is typically seen in PRP. Another distinct difference between platelet-rich plasma and platelet-rich fibrin is a higher concentration of platelets in a single pass within the PRF final product.
As opposed to PRP, PRF is extremely simple. There are no anticoagulants, no need for thrombin additives. Because PRF is performed according to a completely natural process. This fact alone has important implications for the choice of PRF over PRP, especially in dental settings.
Fibrin is a biological scaffold that forms in response to an injury anywhere in the body. Platelets normally circulate within the blood and will bind to a scaffold of fibrin. When platelets bind to the fibrin scaffold, they become activated and release growth factors from tiny ‘granules.’ These growth factors start the wound healing process by creating new skin cells, collagen and blood vessels. PRF appears to target the same issues as PRP, but it releases the growth factors over time, which means it could have longer-term benefits. The growth factors are what stimulate the stem cells that improve collagen and elastin in the skin. The platelets in PRF are thought to survive better than those in PRP, and therefore promote faster healing.
Platelet-rich plasma (PRP) is a platelet concentrate that has been used widely to accelerate soft-tissue and hard-tissue healing. Platelet-rich fibrin (PRF) was first described by Choukroun et al. in France. It has been referred to as a second-generation platelet concentrate, which has been shown to have several advantages over traditionally prepared PRP.
“The science is pretty clear: for internal medicine, the choice is PRP. For dermatology and orofacial, the best choice is PRF.”
Current Parmaceutical Biotechnology, 2012, 13, Dohan and Al:
Current Knowledge and Perspectives for the use of PRP and PRF in oral and Maxillofacial Surgery
PRF eliminates the redundant process of adding anticoagulant as well as the need to neutralize it. The addition of bovine-derived thrombin to promote conversion of fibrinogen to fibrin in PRP is also eliminated. The elimination of these steps considerably reduces biochemical handling of blood as well as risks associated with the use of bovine-derived thrombin. The conversion of fibrinogen into fibrin takes place slowly with small quantities of physiologically available thrombin present in the blood sample itself.
Some argue that PRP enriched with large number of growth factors (a portion of it may even be excess) produce short-term effect and so is less desirable than a PRF whose release is slower and thus more beneficial in the long run.
It could be some time before PRF is “mainstream,” but it’s been studied in wound healing trials and shown to be safe. Right now it’s primarily being used in the dental area for implants and bone healing, but it’s an interesting field and the obvious next step in the evolution of natural rejuvenation.
PRF belongs to a new generation of platelet concentrate, it represents a new step in the platelet gel therapeutic concepts with simplified processing with no artificial biochemical modification.
How are PRP and PRF created?
PRP and PRF are created by drawing a small sample of your blood at the time of your appointment. This sample of your blood is placed in a centrifuge and spun for a specific time and at a specific rate of spin. Regenerative properties of you blood like stem cells and other growth factors are separated out and then prepared to be used for your treatment.
Is PRP and PRF rejuvenation safe?
Yes. PRF is made from your own blood and is free of any additional additive. PRF is 100% natural and 100% you.
Who may be a candidate for PRP and PRF rejuvenation?
An ideal candidate is someone who is looking for an all natural treatment to correct lines, skin tone, and uneven skin texture. Our team will meet with you and review your medical history. We will also discuss expectations and determine if PRF rejuvenation is something that would benefit you.
Are PRP and PRF treatments painful?
The drawing of your blood requires a stick and can be a little uncomfortable. The laser treatment is a gentile resurfacing of the skin. This allows the skin to be prepared to receive the PRF. There is a sensation that is associated with the laser treatment. Most people do not experience pain.
How much improvement can I expect from PRF Facial and how long will it last?
Results vary from patient to patient. Improvement can vary depending on amount of sun damage, personal skin care habits, health, etc. Most people see a subtle improvement that continues for 3-4 weeks. You will see optimal results at around 8 weeks. We suggest you wait 8 weeks between treatments. Again, this can vary depending on skin health.
What should I expect after the PRF procedure?
You may have some minor redness when you leave the office. We always start off with a very mild treatment to see how your skin reacts. You may have some puffiness and redness the following day. Around Day 3 or 4 you may see some flaking. Your skin will begin to look more even and smooth after the flaking.